Not Doing Well

I have a ton of physce issues and I'm on a pretty heavy regamin of drugs. I have been a stay-at-home part-time employer doing numerous things mostly IT works. My wife is a salon manager and her salon is completely closed. I guess the question that I have is I've gone 2 years of life isolation and not that she's here with me and it's only been two weeks it's freaking her out and her freakouts are freaking me out it's so horrible and I feel so bad for her she's my wife I don't know what I can do to make things better for her. If anyone has advice let me know